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Journal / Bioengineering / Implantación subretiniana de EPR en un portador…
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Bioengineering
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JoVE Journal Bioengineering
Implantación subretiniana de EPR en un portador en minicerdos
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Implantación subretiniana de EPR en un portador en minicerdos: pautas para preparaciones preoperatorias, técnicas quirúrgicas y cuidados postoperatorios

Article DOI: 10.3791/63505-v • 11:06 min • November 11th, 2022
November 11th, 2022 •
*1,2, *3, 4, 4, 4, 5,6, 5,6, 5,6, 5,6, 5,6, 5, 5, 5, 5, 7, 8, 9, 10, 11, 1, 1, 5, *8, *5
1Eye Clinic, Department of Ophthalmology, University Hospital Giessen and Marburg GmbH, 2Karl Landsteiner Institute for Retinal Research and Imaging, 3Department of Ophthalmology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, 4Institute of Macromolecular Chemistry, Czech Academy of Sciences, 5Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 6Department of Cell Biology, Faculty of Science, Charles University, 7Institute of Experimental Medicine, Czech Academy of Sciences, 8Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 9Moorfields Eye Hospitals UAE, 10Stem Cell Therapies in Neurodegenerative Diseases Lab, Research Center “Principe Felipe”, 11Eye Center Donaustadt, Department of Ophthalmology, Sigmund Freud University
* These authors contributed equally

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La implantación subretiniana de epitelio pigmentado retiniano (EPR) es uno de los enfoques más prometedores para el tratamiento de enfermedades degenerativas de la retina. Sin embargo, el rendimiento de los estudios preclínicos en modelos animales de ojo grande sigue siendo un desafío. Este informe presenta pautas para el trasplante subretiniano de EPR en un portador de células en minicerdos.

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Bioingeniería Número 189 Degeneración macular relacionada con la edad epitelio pigmentado de la retina EPR modelo animal de ojo grande minicerdos vitrectomía pars plana VPP portador celular cirugía in vivo cuidados preoperatorios y postoperatorios
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