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Journal / Bioengineering / Impianto sottoretinico di RPE su un portatore in…
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Impianto sottoretinico di RPE su un portatore in maialini
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Impianto sottoretinico di RPE su un portatore in maialini: linee guida per preparazioni preoperatorie, tecniche chirurgiche e cure postoperatorie

Article DOI: 10.3791/63505-v • 11:06 min • November 11th, 2022
November 11th, 2022 •
*1,2, *3, 4, 4, 4, 5,6, 5,6, 5,6, 5,6, 5,6, 5, 5, 5, 5, 7, 8, 9, 10, 11, 1, 1, 5, *8, *5
1Eye Clinic, Department of Ophthalmology, University Hospital Giessen and Marburg GmbH, 2Karl Landsteiner Institute for Retinal Research and Imaging, 3Department of Ophthalmology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, 4Institute of Macromolecular Chemistry, Czech Academy of Sciences, 5Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 6Department of Cell Biology, Faculty of Science, Charles University, 7Institute of Experimental Medicine, Czech Academy of Sciences, 8Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 9Moorfields Eye Hospitals UAE, 10Stem Cell Therapies in Neurodegenerative Diseases Lab, Research Center “Principe Felipe”, 11Eye Center Donaustadt, Department of Ophthalmology, Sigmund Freud University
* These authors contributed equally

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L'impianto sottoretinico dell'epitelio pigmentato retinico (RPE) è uno degli approcci più promettenti per il trattamento delle malattie degenerative della retina. Tuttavia, le prestazioni degli studi preclinici su modelli animali di grandi occhi rimangono impegnative. Questo rapporto presenta le linee guida per il trapianto sottoretinico di RPE su un vettore cellulare in maialini.

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Bioingegneria Numero 189 Degenerazione maculare legata all'età epitelio pigmentato retinico RPE modello animale con occhio grande minipigs vitrectomia pars plana PPV carrier cellulare chirurgia in vivo cure preoperatorie e postoperatorie
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