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Journal / Bioengineering / Subretinal implantation af RPE på en bærer hos…
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Bioengineering
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JoVE Journal Bioengineering
Subretinal implantation af RPE på en bærer hos minigrise
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Subretinal implantation af RPE på en bærer hos minigrise: retningslinjer for præoperative præparater, kirurgiske teknikker og postoperativ pleje

Article DOI: 10.3791/63505-v • 11:06 min • November 11th, 2022
November 11th, 2022 •
*1,2, *3, 4, 4, 4, 5,6, 5,6, 5,6, 5,6, 5,6, 5, 5, 5, 5, 7, 8, 9, 10, 11, 1, 1, 5, *8, *5
1Eye Clinic, Department of Ophthalmology, University Hospital Giessen and Marburg GmbH, 2Karl Landsteiner Institute for Retinal Research and Imaging, 3Department of Ophthalmology, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University in Prague, 4Institute of Macromolecular Chemistry, Czech Academy of Sciences, 5Institute of Animal Physiology and Genetics, Czech Academy of Sciences, 6Department of Cell Biology, Faculty of Science, Charles University, 7Institute of Experimental Medicine, Czech Academy of Sciences, 8Center for Eye Research, Department of Ophthalmology, Oslo University Hospital and Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 9Moorfields Eye Hospitals UAE, 10Stem Cell Therapies in Neurodegenerative Diseases Lab, Research Center “Principe Felipe”, 11Eye Center Donaustadt, Department of Ophthalmology, Sigmund Freud University
* These authors contributed equally

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Den subretinale implantation af retinal pigmenteret epitel (RPE) er en af de mest lovende tilgange til behandling af degenerative retinale sygdomme. Udførelsen af prækliniske undersøgelser af dyremodeller med store øjne er dog fortsat udfordrende. Denne rapport præsenterer retningslinjer for subretinal transplantation af RPE på en cellebærer til minigrise.

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Bioengineering udgave 189 Aldersrelateret makuladegeneration retinal pigmenteret epitel RPE dyremodel med store øjne minigrise pars plana vitrektomi PPV cellebærer in vivo-kirurgi præoperativ og postoperativ pleje
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