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Journal / Immunology and Infection / Induktion af parodontitis via en kombination af…
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Immunology and Infection
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JoVE Journal Immunology and Infection
Induktion af parodontitis via en kombination af ligatur og lipopolysaccharidinjektion i en rottemodel
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Induktion af parodontitis via en kombination af ligatur og lipopolysaccharidinjektion i en rottemodel

Article DOI: 10.3791/64842-v • 06:14 min • February 17th, 2023
February 17th, 2023 •
1,2, 1, 1,2,3, 1,2,4,5, 1,2,4,5
1Group of Cell Therapy and Tissue Engineering, Research Institute on Health Sciences (IUNICS), University of the Balearic Islands (UIB), 2Balearic Islands Health Research Institute (IdISBa), 3Preclinical Research Department, Labo'Life España, 4Departament de Biologia Fonamental i Ciències de la Salut, UIB, 5ADEMA School of Dentistry, UIB

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I denne undersøgelse præsenteres en rottemodel for induktion af parodontitis via en kombination af retentiv ligatur og gentagne injektioner af lipopolysaccharid afledt af Porphyromonas gingivalis, over 14 dage omkring de første maksillære molarer. Ligerings- og LPS-injektionsteknikkerne var effektive til at inducere peridontitis, hvilket resulterede i alveolært knogletab og betændelse.

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Immunologi og infektion nummer 192
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