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Journal / Immunology and Infection / 在大鼠模型中通过结扎和脂多糖注射的组合 诱导…
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Immunology and Infection
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JoVE Journal Immunology and Infection
在大鼠模型中通过结扎和脂多糖注射的组合 诱导 牙周炎
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在大鼠模型中通过结扎和脂多糖注射的组合 诱导 牙周炎

Article DOI: 10.3791/64842-v • 06:14 min • February 17th, 2023
February 17th, 2023 •
1,2, 1, 1,2,3, 1,2,4,5, 1,2,4,5
1Group of Cell Therapy and Tissue Engineering, Research Institute on Health Sciences (IUNICS), University of the Balearic Islands (UIB), 2Balearic Islands Health Research Institute (IdISBa), 3Preclinical Research Department, Labo'Life España, 4Departament de Biologia Fonamental i Ciències de la Salut, UIB, 5ADEMA School of Dentistry, UIB

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在这项研究中，通过保留结扎和重复注射源自牙龈卟啉单胞菌的脂多糖的组合，在第上颌磨牙周围超过14天，提出了诱导牙周炎的大鼠模型。结扎和LPS注射技术可有效诱发牙周炎，导致牙槽骨质流失和炎症。

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免疫学与感染，第192期，
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