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Journal / Biochemistry / Pinzette magnetiche ad alta velocità per misure…
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Pinzette magnetiche ad alta velocità per misure nanomeccaniche su elementi sensibili alla forza
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Pinzette magnetiche ad alta velocità per misure nanomeccaniche su elementi sensibili alla forza

Article DOI: 10.3791/65137-v • 08:50 min • May 12th, 2023
May 12th, 2023 •
*1, *1, 1, 2,3, 2,3, 1,4
1Department of Physics, Pohang University of Science and Technology (POSTECH), 2School of Biological Sciences, Seoul National University, 3Institute for Molecular Biology and Genetics, Seoul National University, 4School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)
* These authors contributed equally

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Qui, descriviamo una configurazione di pinzette magnetiche ad alta velocità che esegue misurazioni nanomeccaniche su biomolecole sensibili alla forza alla velocità massima di 1,2 kHz. Presentiamo la sua applicazione a forcine di DNA e complessi SNARE come sistemi modello, ma sarà applicabile anche ad altre molecole coinvolte in eventi meccanobiologici.

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Questo mese in JoVE Numero 195 pinzette magnetiche ad alta velocità spettroscopia di forza a singola molecola forcina per capelli del DNA complesso SNARE
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