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Somatiske genom-manipulerede musemodeller ved hjælp af in vivo mikroinjektion og elektroporation
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Somatiske genom-manipulerede musemodeller ved hjælp af in vivo mikroinjektion og elektroporation

Article DOI: 10.3791/65131-v • 08:06 min • May 5th, 2023
May 5th, 2023 •
1,2, 1,3, 1,2,3
1Rosalind and Morris Goodman Cancer Research Institute, McGill University, 2Department of Human Genetics, McGill University, 3McGill Integrated Core for Animal Modeling (MICAM), McGill University

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Denne protokol beskriver mikroinjektion og in vivo-elektroporation til regionalt begrænset CRISPR-medieret genomredigering i museovidukten.

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Kræftforskning udgave 195 CRISPR/Cas genomredigering æggeleder ovidukt kræft i æggestokkene in vivo kræftmodellering
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