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Overvåking av signalresponser på målet hos sebrafisk hos larver - Z-REX avdekker presise mekanismer for elektrofile stoffer og metabolitter
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Overvåking av signalresponser på målet hos sebrafisk hos larver - Z-REX avdekker presise mekanismer for elektrofile stoffer og metabolitter

Article DOI: 10.3791/64846-v • 05:28 min • June 2nd, 2023
June 2nd, 2023 •
1, 1, 2, 3, 4, 1
1Swiss Federal Institute of Technology Lausanne (EPFL), 2Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, 3Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, 4University of Lausanne (UNIL)

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Sebrafisk rettet mot reaktive elektrofiler og oksidanter (Z-REX) er en kjemisk biologibasert metode for undersøkelse av reaktiv småmolekylær signalering. Denne teknikken kan brukes på levende fisk av forskjellige utviklingsstadier. Her kobler vi standardanalyser i sebrafisk med Z-REX for analyse av signalveier.

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