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Journal / Cancer Research / 建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试…
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Cancer Research

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JoVE Journal Cancer Research
建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试
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Immunophenotyping of Orthotopic Homograft (Syngeneic) of Murine Primary KPC Pancreatic Ductal Adenocarcinoma by Flow Cytometry
Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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建立胰腺癌斑马鱼患者来源的异种移植物进行化学敏感性测试

Article DOI: 10.3791/63744-v • 06:59 min • May 12th, 2023
May 12th, 2023 •
1, 2, 1, 2, 1
1Department of Biology, University of Pisa, 2General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa

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临床前模型旨在提高癌症生物学知识并预测治疗效果。本文描述了基于斑马鱼的患者来源的带有肿瘤组织碎片的异种移植物（zPDX）的产生。zPDXs用化疗治疗，根据移植组织的细胞凋亡评估其治疗效果。

Tags

癌症研究，第195期，斑马鱼头像，临床前模型，联合临床试验，肿瘤移植，化学敏感性，全安装免疫荧光
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