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Journal / Medicine / 建立大鼠永久性颈静脉插管的显微外科技能，用于口服药物的连续血液采样…
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建立大鼠永久性颈静脉插管的显微外科技能，用于口服药物的连续血液采样
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建立大鼠永久性颈静脉插管的显微外科技能，用于口服药物的连续血液采样

Article DOI: 10.3791/63167-v • 08:28 min • December 14th, 2021
December 14th, 2021 •
*1, *1, 1, 1, 1, 1
1Xi'an Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Medical Research, Northwestern Polytechnical University
* These authors contributed equally

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详细的显微外科技术被证明可以建立一个长期的颈静脉插管大鼠模型，用于同一动物的序贯血液采集。在大鼠的恢复阶段监测生理和血液学参数。该模型已应用于研究口服多酚的药代动力学，而不会诱导动物应激。

Tags

撤回，第178期，JVC模型，血管，导管植入，采血，动物护理，生理监测，血液学测试，药代动力学，天然苯酚
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