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JoVE Journal Medicine
implantation af kombinerede telemetriske EKG- og blodtrykstransmittere til bestemmelse af spontan baroreflexfølsomhed hos bevidste mus
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implantation af kombinerede telemetriske EKG- og blodtrykstransmittere til bestemmelse af spontan baroreflexfølsomhed hos bevidste mus

Article DOI: 10.3791/62101-v • 09:56 min • February 14th, 2021
February 14th, 2021 •
1, 1, 1, 1, 1,2, 3, 1,2
1Center for Integrated Protein Science (CIPS-M) and Center for Drug Research, Department of Pharmacy, Ludwig-Maximilians-Universität München, 2German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, 3Hannover Medical School, Institute for Neurophysiology

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Baroreflex er en hjertefrekvensreguleringsmekanisme af det autonome nervesystem som reaktion på blodtryksændringer. Vi beskriver en kirurgisk teknik til implantering af telemetrisendere til kontinuerlig og samtidig måling af elektrokardiogram og blodtryk hos mus. Dette kan bestemme spontan baroreflexfølsomhed, en vigtig prognostisk markør for hjerte-kar-sygdomme.

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Medicin udgave 168 baroreceptorfølsomhed baroreflex telemetri arterielt blodtryk elektrokardiogram EKG sinoatriale knudefunktion autonomt nervesystem diagnostisk markør hjerte-kar-sygdom musemodel
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