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Journal / Immunology and Infection / マウスにおけるガードネレラ膣膀胱曝露によって引き起こされる再発性大腸菌尿路感染症…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
マウスにおけるガードネレラ膣膀胱曝露によって引き起こされる再発性大腸菌尿路感染症
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マウスにおけるガードネレラ膣膀胱曝露によって引き起こされる再発性大腸菌尿路感染症

Article DOI: 10.3791/61967-v • 08:53 min • December 4th, 2020
December 4th, 2020 •
1,2,6, 3,7, 1,2,4,8, 2,5
1Department of Molecular Microbiology, Washington University School of Medicine in Saint Louis, 2Center for Women’s Infectious Disease Research, Washington University School of Medicine in Saint Louis, 3Center for Cellular Imaging, Washington University School of Medicine in Saint Louis, 4Department of Obstetrics and Gynecology, Washington University School of Medicine in Saint Louis, 5Department of Pediatrics, Washington University School of Medicine in Saint Louis, 6Fred Hutchinson Cancer Research Center, 7TESCAN USA, Inc., 8University of California San Diego

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尿路病原性 大腸菌 (UPEC)経尿道接種のマウスモデルにより、潜伏細胞内膀胱リザーバを確立し、その後の再発性UPEC UTIを誘導するための G.膣への膀胱 曝露が実証される。また、細菌の列挙、尿細胞診、および走査型電子顕微鏡のためのin situ膀胱固定および処理も実証されている。

Tags

免疫学と感染症 第166号 UTI 再発性UTI 潜伏感染 細菌性膣炎 経尿道カテーテル 膣 尿 嫌気性 膀胱 腎臓 尿中微生物叢 膣内微生物叢 走査型電子顕微鏡
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