James D. McCully Department of Cardiac Surgery, Boston Children’s Hospital Harvard Medical School Biography Publications Institution JoVE Articles James D. McCully has not added a biography. If you are James D. McCully and would like to personalize this page please email our Author Liaison for assistance. Publications Autologous Mitochondrial Transplantation for Cardiogenic Shock in Pediatric Patients Following Ischemia-reperfusion Injury The Journal of Thoracic and Cardiovascular Surgery. Dec, 2020 | Pubmed ID: 33349443 A Multi-Mode System for Myocardial Functional and Physiological Assessment During Ex Situ Heart Perfusion The Journal of Extra-corporeal Technology. Dec, 2020 | Pubmed ID: 33343033 Autogenous Mitochondria Transplantation for Treatment of Right Heart Failure The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020 | Pubmed ID: 32919774 Commentary: Independent, Additive or Linked: A Novel Therapeutic Option for the Treatment of Pulmonary Hypertension May Involve More Than One Mechanism The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020 | Pubmed ID: 32919766 Mitochondrial Transplantation for Myocardial Protection in Ex-situ‒perfused Hearts Donated After Circulatory Death The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Jun, 2020 | Pubmed ID: 32703639 Mitochondrial Transplantation by Intra-arterial Injection for Acute Kidney Injury American Journal of Physiology. Renal Physiology. 09, 2020 | Pubmed ID: 32686525 Letter by McCully Et Al Regarding Article, "Mitochondria Do Not Survive Calcium Overload" Circulation Research. 04, 2020 | Pubmed ID: 32271682 Reply: Intracoronary Delivery of Mitochondria to Prevent Ischemia-Reperfusion Injury: Challenging Pathway From Bench to Bedside JACC. Basic to Translational Science. Feb, 2020 | Pubmed ID: 32140627 Mitochondrial Transplantation for Myocardial Protection in Diabetic Hearts European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. 05, 2020 | Pubmed ID: 31782771 Mitochondrial Transplantation Enhances Murine Lung Viability and Recovery After Ischemia-reperfusion Injury American Journal of Physiology. Lung Cellular and Molecular Physiology. 01, 2020 | Pubmed ID: 31693391 Preischemic Autologous Mitochondrial Transplantation by Intracoronary Injection for Myocardial Protection The Journal of Thoracic and Cardiovascular Surgery. Aug, 2020 | Pubmed ID: 31564546 Delayed Transplantation of Autologous Mitochondria for Cardioprotection in a Porcine Model The Annals of Thoracic Surgery. 03, 2020 | Pubmed ID: 31421103 Mitochondrial Transplantation Ameliorates Acute Limb ischemia Journal of Vascular Surgery. 03, 2020 | Pubmed ID: 31353269 A Novel Biological Strategy for Myocardial Protection by Intracoronary Delivery of Mitochondria: Safety and Efficacy JACC. Basic to Translational Science. Dec, 2019 | Pubmed ID: 31909298 Mitochondrial Transplantation Prolongs Cold Ischemia Time in Murine Heart Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 01, 2019 | Pubmed ID: 30391192 Alloreactivity and Allorecognition of Syngeneic and Allogeneic Mitochondria Mitochondrion. 05, 2019 | Pubmed ID: 29588218 Transit and Integration of Extracellular Mitochondria in Human Heart Cells Scientific Reports. 12, 2017 | Pubmed ID: 29234096 Invited Commentary The Annals of Thoracic Surgery. 10, 2017 | Pubmed ID: 28935303 Mitochondrial Transplantation in Myocardial Ischemia and Reperfusion Injury Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28551809 Mitochondrial Transplantation: From Animal Models to Clinical Use in Humans Mitochondrion. 05, 2017 | Pubmed ID: 28342934 Myocardial Rescue with Autologous Mitochondrial Transplantation in a Porcine Model of Ischemia/reperfusion The Journal of Thoracic and Cardiovascular Surgery. 04, 2017 | Pubmed ID: 27938904 Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection PloS One. 2016 | Pubmed ID: 27500955 Mitochondrial Transplantation for Therapeutic Use Clinical and Translational Medicine. Mar, 2016 | Pubmed ID: 27130633 Actin-dependent Mitochondrial Internalization in Cardiomyocytes: Evidence for Rescue of Mitochondrial Function Biology Open. Apr, 2015 | Pubmed ID: 25862247 Superparamagnetic Iron Oxide Nanoparticles Function As a Long-term, Multi-modal Imaging Label for Non-invasive Tracking of Implanted Progenitor Cells PloS One. 2014 | Pubmed ID: 25250622 Transplantation of Autologously Derived Mitochondria Protects the Heart from Ischemia-reperfusion Injury American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2013 | Pubmed ID: 23355340 Pressure-overload Hypertrophy of the Developing Heart Reveals Activation of Divergent Gene and Protein Pathways in the Left and Right Ventricular Myocardium American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2013 | Pubmed ID: 23262132 Microarray and Proteomic Analysis of the Cardioprotective Effects of Cold Blood Cardioplegia in the Mature and Aged Male and Female Physiological Genomics. Nov, 2012 | Pubmed ID: 22968637 Differential Expression of Collagen Type V and XI Alpha-1 in Human Ascending Thoracic Aortic Aneurysms The Annals of Thoracic Surgery. Aug, 2009 | Pubmed ID: 19632402 Transcriptomic and Proteomic Analysis of Global Ischemia and Cardioprotection in the Rabbit Heart Physiological Genomics. Jul, 2009 | Pubmed ID: 19454556 Injection of Isolated Mitochondria During Early Reperfusion for Cardioprotection American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2009 | Pubmed ID: 18978192 Cardioplegia and Diazoxide Modulate STAT3 Activation and DNA Binding The Annals of Thoracic Surgery. Oct, 2007 | Pubmed ID: 17888982 Age- and Gender-related Differences in Mitochondrial Oxygen Consumption and Calcium with Cardioplegia and Diazoxide The Annals of Thoracic Surgery. Mar, 2007 | Pubmed ID: 17307466 Reduction and Redistribution of Gap and Adherens Junction Proteins After Ischemia and Reperfusion The Annals of Thoracic Surgery. Oct, 2006 | Pubmed ID: 16996956 Age- and Gender-related Differences in Ischemia/reperfusion Injury and Cardioprotection: Effects of Diazoxide The Annals of Thoracic Surgery. Jul, 2006 | Pubmed ID: 16798201 Differential Contribution of Necrosis and Apoptosis in Myocardial Ischemia-reperfusion Injury American Journal of Physiology. Heart and Circulatory Physiology. May, 2004 | Pubmed ID: 14715509 Mitochondrial ATP-sensitive Potassium Channels in Surgical Cardioprotection Archives of Biochemistry and Biophysics. Dec, 2003 | Pubmed ID: 14654062 Mitochondrial DNA Deletions in Coronary Artery Bypass Grafting Patients European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Nov, 2003 | Pubmed ID: 14583312 The Mitochondrial K(ATP) Channel and Cardioprotection The Annals of Thoracic Surgery. Feb, 2003 | Pubmed ID: 12607710 Diazoxide Amelioration of Myocardial Injury and Mitochondrial Damage During Cardiac Surgery The Annals of Thoracic Surgery. Dec, 2002 | Pubmed ID: 12643408 A Novel Peroxynitrite Decomposer Catalyst (FP-15) Reduces Myocardial Infarct Size in an in Vivo Peroxynitrite Decomposer and Acute Ischemia-reperfusion in Pigs The Annals of Thoracic Surgery. Oct, 2002 | Pubmed ID: 12400769 Myocardial Protection by PJ34, a Novel Potent Poly (ADP-ribose) Synthetase Inhibitor The Annals of Thoracic Surgery. Feb, 2002 | Pubmed ID: 11845877 Model of Ischemia and Reperfusion Injury in Rabbits Victor S. Alemany*1, Dominic P. Recco*1, Sitaram M. Emani1, Pedro J. del Nido1, James D. McCully1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 64752 Medicine A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion Ilias P. Doulamis1, Alvise Guariento1, Mossab Y. Saeed1, Rio S. Nomoto1, Thomas Duignan1, Pedro J. del Nido1, James D. McCully1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 62230 Medicine Rapid Isolation And Purification Of Mitochondria For Transplantation By Tissue Dissociation And Differential Filtration Janine M. Preble1, Christina A. Pacak2, Hiroshi Kondo1, Allison A. MacKay2, Douglas B. Cowan2, James D. McCully1 1Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 2Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital and Department of Anesthesia, Harvard Medical School JoVE 51682 Biology
Model of Ischemia and Reperfusion Injury in Rabbits Victor S. Alemany*1, Dominic P. Recco*1, Sitaram M. Emani1, Pedro J. del Nido1, James D. McCully1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 64752 Medicine
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion Ilias P. Doulamis1, Alvise Guariento1, Mossab Y. Saeed1, Rio S. Nomoto1, Thomas Duignan1, Pedro J. del Nido1, James D. McCully1 1Department of Cardiac Surgery, Boston Children’s Hospital, Harvard Medical School JoVE 62230 Medicine
Rapid Isolation And Purification Of Mitochondria For Transplantation By Tissue Dissociation And Differential Filtration Janine M. Preble1, Christina A. Pacak2, Hiroshi Kondo1, Allison A. MacKay2, Douglas B. Cowan2, James D. McCully1 1Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, 2Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital and Department of Anesthesia, Harvard Medical School JoVE 51682 Biology
