Alonso Heredia Institute of Human Virology, School of Medicine University of Maryland Biography Publications Institution JoVE Articles Alonso Heredia has not added a biography. If you are Alonso Heredia and would like to personalize this page please email our Author Liaison for assistance. Publications Glycan-dependent HIV-specific Neutralizing Antibodies Bind to Cells of Uninfected Individuals The Journal of Clinical Investigation. Nov, 2019 | Pubmed ID: 31589168 CCR5 Inhibitors and HIV-1 Infection Journal of AIDS and HIV Treatment. 2019 | Pubmed ID: 31414081 Suppression of Active HIV-1 Infection in CD34 Hematopoietic Humanized NSG Mice by a Combination of Combined Antiretroviral Therapy and CCR5 Targeting Drugs AIDS Research and Human Retroviruses. Aug, 2019 | Pubmed ID: 31099257 Role of the Inflammasomes in HIV-associated Neuroinflammation and Neurocognitive Disorders Experimental and Molecular Pathology. Jun, 2019 | Pubmed ID: 30922769 Disparate Effects of Cytotoxic Chemotherapy on the Antiviral Activity of Antiretroviral Therapy: Implications for Treatments of HIV-infected Cancer Patients Antiviral Therapy. 2019 | Pubmed ID: 30574873 Targeting of CDK9 with Indirubin 3'-monoxime Safely and Durably Reduces HIV Viremia in Chronically Infected Humanized Mice PloS One. 2017 | Pubmed ID: 28817720 Monotherapy with Either Dolutegravir or Raltegravir Fails to Durably Suppress HIV Viraemia in Humanized Mice The Journal of Antimicrobial Chemotherapy. 09, 2017 | Pubmed ID: 28637235 Synergistic Inhibition of R5 HIV-1 by the Fusion Protein (FLSC) IgG1 Fc and Maraviroc in Primary Cells: Implications for Prevention and Treatment Current HIV Research. 2016 | Pubmed ID: 26354735 A Novel Small-molecule Inhibitor of HIV-1 Entry Drug Design, Development and Therapy. 2015 | Pubmed ID: 26491257 Targeting of MTOR Catalytic Site Inhibits Multiple Steps of the HIV-1 Lifecycle and Suppresses HIV-1 Viremia in Humanized Mice Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26170311 Impact of HIV on Lung Tumorigenesis in an Animal Model AIDS (London, England). Mar, 2015 | Pubmed ID: 25611150 Binding of Fusion Protein FLSC IgG1 to CCR5 is Enhanced by CCR5 Antagonist Maraviroc Antiviral Research. Dec, 2014 | Pubmed ID: 25453341 Indirubin 3'-monoxime, from a Chinese Traditional Herbal Formula, Suppresses Viremia in Humanized Mice Infected with Multidrug-resistant HIV AIDS Research and Human Retroviruses. May, 2014 | Pubmed ID: 24401082 Targeting Host Nucleotide Biosynthesis with Resveratrol Inhibits Emtricitabine-resistant HIV-1 AIDS (London, England). Jan, 2014 | Pubmed ID: 24326355 Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-resistant HIV-1 The Journal of Infectious Diseases. Dec, 2013 | Pubmed ID: 23922365 Synergistic Inhibition of R5 HIV-1 by Maraviroc and CCR5 Antibody HGS004 in Primary Cells: Implications for Treatment and Prevention AIDS (London, England). Jun, 2011 | Pubmed ID: 21505306 CCR5 Antibodies HGS004 and HGS101 Preferentially Inhibit Drug-bound CCR5 Infection and Restore Drug Sensitivity of Maraviroc-resistant HIV-1 in Primary Cells Virology. Mar, 2011 | Pubmed ID: 21232779 Pharmacotherapy of HIV-1 Infection: Focus on CCR5 Antagonist Maraviroc Clinical Medicine. Therapeutics. 2009 | Pubmed ID: 19920876 Rapamycin Enhances Aplaviroc Anti-HIV Activity: Implications for the Clinical Development of Novel CCR5 Antagonists Antiviral Research. Jul, 2009 | Pubmed ID: 19501260 Enzymatic Glycosylation of Triazole-linked GlcNAc/Glc-peptides: Synthesis, Stability and Anti-HIV Activity of Triazole-linked HIV-1 Gp41 Glycopeptide C34 Analogues Chembiochem : a European Journal of Chemical Biology. May, 2009 | Pubmed ID: 19353609 Reduction of CCR5 with Low-dose Rapamycin Enhances the Antiviral Activity of Vicriviroc Against Both Sensitive and Drug-resistant HIV-1 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19075241 An Alteration of Human Immunodeficiency Virus Gp41 Leads to Reduced CCR5 Dependence and CD4 Independence Journal of Virology. Jun, 2008 | Pubmed ID: 18353949 Rapamycin Reduces CCR5 MRNA Levels in Macaques: Potential Applications in HIV-1 Prevention and Treatment AIDS (London, England). Oct, 2007 | Pubmed ID: 17885304 CCR5 Density Levels on Primary CD4 T Cells Impact the Replication and Enfuvirtide Susceptibility of R5 HIV-1 AIDS (London, England). Jun, 2007 | Pubmed ID: 17545708 Rapamycin Reduces CCR5 Density Levels on CD4 T Cells, and This Effect Results in Potentiation of Enfuvirtide (T-20) Against R5 Strains of Human Immunodeficiency Virus Type 1 in Vitro Antimicrobial Agents and Chemotherapy. Jul, 2007 | Pubmed ID: 17485501 HIV-1 Natural Viral Suppressors: Control of Viral Replication in the Absence of Therapy AIDS (London, England). Feb, 2007 | Pubmed ID: 17301571 Indirubin-3'-monoxime, a Derivative of a Chinese Antileukemia Medicine, Inhibits P-TEFb Function and HIV-1 Replication AIDS (London, England). Dec, 2005 | Pubmed ID: 16284457 In Vitro Suppression of Latent HIV-1 Activation by Vitamin E: Potential Clinical Implications AIDS (London, England). May, 2005 | Pubmed ID: 15867501 Modification and Structure-activity Relationship of a Small Molecule HIV-1 Inhibitor Targeting the Viral Envelope Glycoprotein Gp120 Organic & Biomolecular Chemistry. May, 2005 | Pubmed ID: 15858664 Resveratrol Glucuronides As the Metabolites of Resveratrol in Humans: Characterization, Synthesis, and Anti-HIV Activity Journal of Pharmaceutical Sciences. Oct, 2004 | Pubmed ID: 15349955 Synthetic Bivalent CD4-mimetic Miniproteins Show Enhanced Anti-HIV Activity over the Monovalent Miniprotein Bioconjugate Chemistry. Jul-Aug, 2004 | Pubmed ID: 15264865 Design and Synthesis of Alpha Gal-conjugated Peptide T20 As Novel Antiviral Agent for HIV-immunotargeting Organic & Biomolecular Chemistry. Mar, 2004 | Pubmed ID: 14985805 Induction of G1 Cycle Arrest in T Lymphocytes Results in Increased Extracellular Levels of Beta-chemokines: a Strategy to Inhibit R5 HIV-1 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12644703 Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models Federico Perdomo-Celis1,2, Sandra Medina-Moreno1, Alonso Heredia1, Harry Davis1, Joseph Bryant1, Juan Carlos Zapata1 1Institute of Human Virology, School of Medicine, University of Maryland, 2Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia JoVE 60315 Immunology and Infection
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models Federico Perdomo-Celis1,2, Sandra Medina-Moreno1, Alonso Heredia1, Harry Davis1, Joseph Bryant1, Juan Carlos Zapata1 1Institute of Human Virology, School of Medicine, University of Maryland, 2Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia JoVE 60315 Immunology and Infection