Chapter 11

Meiosis

What is Meiosis?
Meiosis is the process by which diploid cells divide to produce haploid daughter cells. In humans, each diploid cell contains 46 chromosomes, half…
Meiosis I
11.2: Meiosis I
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each…
Meiosis II
11.3: Meiosis II
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23…
Crossing Over
11.4: Crossing Over
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I,…
Chromatin Spread Preparations
11.7: Chromatin Spread Preparations
The process of mammalian oogenesis can be prone to errors. This article describes chromatin spread methods to study chromosome morphology and…
Using FISH to Monitor Chromosome Segregation
11.8: Using FISH to Monitor Chromosome Segregation
Chromosome segregation errors are responsible for the majority of miscarriages and birth defects in humans. This protocol uses Fluorescence in…
Immunofluorescence Staining During Meiosis
11.9: Immunofluorescence Staining During Meiosis
Precise spatial and temporal regulation of the ERK pathway is essential for normal development in C. elegans. In this article, signal duration…